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) enantiomer. As these molecules crystallized in the centrosymmetric House team, the inverse enantiomer was also Similarly existing. The piperidine ring in both equally compounds was inside the chair conformation.
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Benzodiazepine withdrawal might be extreme and most likely existence-threatening. Gradual tapering less than health-related supervision is usually recommended to reduce withdrawal signs or symptoms.
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salt formed an prolonged ribbon parallel on the b –axis (Supporting Information and facts) These structural website motifs are also found in similar congeners which also type hydrogen bonded dimers or ribbons extending parallel for the b-axis.[forty nine]
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